The Canadian entrepreneur has always pushed the boundaries of gene editing, once attempting to turn horses into unicorns. Now she is set on modifying human embryos – something her controversial ex-husband was jailed for doing

On a Friday evening in late April, Cathy Tie, the Canadian serial entrepreneur and self-styled “Biotech Barbie”, is centre stage at New York City’s famous Carnegie Hall, performing Saint-Saens’ Piano Concerto No 2 on a gleaming Steinway grand piano, accompanied by an orchestra. Her floor-length pink tulle gown shimmers with gold sequins; her dark hair cascades in waves over her caped shoulders. The music is passionate, but Tie’s expression is impassive. Her eyes dart between the piano keys and the sheet music in a flurry of concentration, but the rest of her face is totally still. She isn’t lost in the music; she’s focused on the job.

After the last notes ring out, Tie stands up and breaks into a tight smile and a brief bow before walking off stage, only to immediately return to receive the slightly awkward Happy Birthday sung by everyone in the orchestra and auditorium. This is Tie’s 30th birthday party. She has hired Carnegie Hall to mark the occasion. And, as I discover at the cocktail afterparty, most of the people invited to this performance – including me – have either only just met Tie or don’t know her at all.

As flights and hotels sell out and prices soar, supporters go to great lengths to see Gunners face Paris Saint-Germain

Since Arsenal’s euphoric Premier League win last week, it has been a never-ending party in much of north London (apart from in Tottenham, although they had their own cause for celebration). And with Arsenal poised to play in the Uefa Champions League final on Saturday, Gooner fever is about to spread to the continent. So it was not surprising that in Stansted’s departure lounge, about 30 miles north-east of central London, the team’s iconic red-and-white shirts were an unmissable sight on Friday morning.

Most Gunners – or Gooners, as they are colloquially known – were preparing to embark on (mostly indirect) journeys to Budapest, where Arsenal will face Paris Saint-Germain. “We’ll get there by train, plane and automobiles,” said Darren Cornish. The 53-year-old IT manager from Hemel Hampstead was not exaggerating. Arsenal fans the Guardian spoke to plan on trekking to the Hungarian capital via overnight buses and trains from surrounding countries after flights to Budapest spiked following their Premier League victory.

Some Iranians hoped foreign intervention would unseat the regime but instead the US-Israel war has damaged livelihoods and strengthened those in power

As Donald Trump swung this week between threats of new military action against Iran and predictions that a lasting ceasefire deal was imminent, many Iranians were left exhausted and gripped by uncertainty.

Despite the partial lifting of an internet shutdown that began when the war started on 28 February, fears of worsening repression at home have also fuelled pessimism about the future among some of those to whom the Guardian spoke.

A blue micromoon is a rare spectacle, though it’s not as blue or as micro as you might imagine

This weekend the night skies will feature a rare spectacle – a blue micromoon. We take a look at what the phrase means and how to catch a glimpse of the event.

Ailsa, 31, a systems engineer, meets Mike, 35, a paralegal

What were you hoping for?
Good conversation with someone interesting.

They often boast thousands of great works – but who needs that? I can only really engage with one or two before feeling exhausted

Visiting an art gallery always goes the same way for me. I look at one artwork. I look at the next artwork. And then the next. What was the first one again? Was it of a farm? Who knows? I reach the inevitable conclusion: there are simply too many paintings. After about 15 minutes I’ve had enough and don’t want to look at any more art; by the time I reach the gift shop I have a powerful urge to lie face down on the floor and go to sleep.

To be clear: I like art. I grew up drawing and painting, did GCSE art and still paint now. But when I go to a gallery now, hoping that this time I’ll feel something, I’m dismayed by the sheer volume of what’s on offer. The National Gallery displays more than 2,400 artworks and the Louvre up to 4,500 paintings. The New York Met boasts tens of thousands of artworks, but I wouldn’t know. When I visited, the rooms were so monotonous and numerous that I got lost, couldn’t find my friends, asked a security guard for help, went up and down in a lift, sat on a bench and then left early. I do not recall a single piece of art. Seeing as the average viewing time is only 27 seconds, that means an hour’s trip exposes you to a whopping 133 paintings. No wonder I can only remember a handful I’ve seen over the years (and those ones are already famous).

Isabel Brooks is a freelance writer

Trial suggests patients with a low test score could be treated with hormone therapy alone with near-identical outcomes

• ‘Like Christmas’: woman’s relief after test finds she can skip chemotherapy

Millions of women with breast cancer could be spared chemotherapy with a groundbreaking genomic test, according to the results of a trial that could transform healthcare guidelines worldwide.

Treatment for breast cancer, the world’s most prevalent form of the disease, involves surgery to remove tumours. Chemotherapy is then usually recommended when doctors believe there is a risk the disease will return.

Exclusive: Shams Sadiq says officers offered financial inducements and to turn a ‘blind eye’ to certain offences

A cafe owner claims police offered him financial benefits and to turn a “blind eye” to certain low-level offences if he informed on Palestine Action.

Shams (his nickname) Sadiq, who owns two Manchester cafes, said the inducements were offered when he went to collect electronic devices that police had confiscated during his arrest last year in connection with alleged offences relating to the banned direct action group.

Despite government pledges, more than 20 authorities will not allow gullies, citing safety, legal and parking concerns

The energy secretary, Ed Miliband, has said charger gullies to connect electric cars parked on streets will help cut costs for drivers, yet millions of UK households may be unable to use the simple technology because their local councils will still not allow charging cables to cross the pavement.

Despite government promises to “slash red tape” and make it easier to put in gullies, more than 20 local authorities appear to be holding out against them.

Pentagon chief also tells Singapore defence summit of ‘alarm’ at China’s military buildup but says US does not seek ‘needless confrontation’

The US warned on Saturday it was “more than capable” of resuming war with Iran after President Donald Trump said any peace deal must adhere to his red lines, including Tehran never being able to develop nuclear weapons.

The White House had signalled Trump was close to a decision on an initial deal on Friday after weeks of mixed signals in tenuous negotiations, though Tehran denied there was a final agreement on ending the Middle East conflict that has jolted the global economy.